Adenovirus type 4 vaccine virus and tablets - SRA

SRX20098766: Adenovirus type 4 vaccine virus and tablets
1 ILLUMINA (Illumina MiSeq) run: 296,592 spots, 108.4M bases, 54.2Mb downloads

Design: Next-gen sequencing of double-stranded genomic DNA of adenovirus on MiSeq system

Submitted by: Walter Reed Army Institute of Research

Study: Adenovirus type 4 vaccine virus and tablets

PRJNA961906 • SRP434492 • All experiments • All runs

show Abstracthide Abstract

The FDA-approved Adenovirus (Ad) Type 4 and Type 7 vaccine is highly effective and essential in preventing outbreaks of acute respiratory diseases (ARD) in U.S. military recruits. Our next-gen sequencing data revealed the presence of a previously undetected mutant strain of the Ad Type 4 (Ad4) component of the licensed vaccine which contains a single amino acid substitution (P388T) in the pre-terminal protein (pTP).

Sample: Adenovirus type 4 vaccine seed stock Lot 089 (Wyeth)

SAMN34371972 • SRS17429888 • All experiments • All runs

Organism: Human adenovirus E4

Library:

Name: 18000

Instrument: Illumina MiSeq

Strategy: WGS

Source: GENOMIC

Selection: RANDOM

Layout: PAIRED

Runs: 1 run, 296,592 spots, 108.4M bases, 54.2Mb

Run	# of Spots	# of Bases	Size	Published
SRR24303728	296,592	108.4M	54.2Mb	2023-06-26

ID:: 27507596

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